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KMID : 0374919950160030465
Inje Medical Journal
1995 Volume.16 No. 3 p.465 ~ p.476
Modified Rapid Flush Technique for Multiple Organ Procurement from Brain Dead Dono


Abstract
In the era of thriving organ transplantation with advancement in immunosuppression and organ preservation, graft function is a major discriminating factor for the successful organ transplantation. Meanwhile, the shortage of organ donors continues
to be
a major limiting factor for the exploitation of organ transplantation. For harvesting grafts in their best condition from the limited cases of the brain-dead donors, every effeorts should be made during the donor management and the organ
procurement
procedure.
Modified rapid flush technique was delveloped to procure all viable organ from a single brain-dead donor without jeopardy to any of the individual grafts. It is rapid, simple, with satisfactory graft function, and consists of no preliminary
dissection
of the livers or kidneys, in situ rapid core-cooling by infusion of cold preservation solution, ligation of superior mesenteric artery and vein, with subsequent rapid dissection of grafts in a bloodless field.
Our trasplantation team performed multiple organ procurement on five brain-dead donors with modified rapid flush technique, and procured five hearts, five livers and six kidneys, The mean number of organs procured per donor was 3.2. The mean time
needed
to procure each organ was 42, 74, and 92 minutes for the heart, liver, and kidneys, respectively. Initial functions of grafted organ were excellent for all transplanted recipients without immediate postoperative organ dysfunction.
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